WEEKLY REVIEW (Mar.4-11)

Chinese Researchers Advance Solar-driven Biosynthesis
A Chinese research team has developed a strategy to rewire energy flow in biohybrids. It enables industrial microorganisms to directly harness solar energy to drive efficient biosynthesis of high-value energy-rich long-chain compounds. Their study was published in Nature Sustainability.
Promising New Treatment for Alzheimer's Disease
Clearance of abnormal Aβ deposits is a promising Alzheimer's disease therapy, but current anti-Aβ immunotherapies have safety issues. Chinese researchers have developed a new treatment called SPYTACs (synthetic peptide-programmed lysosome-targeting chimeras). It shows fewer side effects and has great therapeutic potential. Their study was published in Cell.
OpenAI Launches GPT-5.4, Its Most Powerful Model
OpenAI recently released GPT-5.4, calling it "our most capable and efficient frontier model for professional work." The model combines advanced reasoning, coding, and agentic workflows into a single frontier model, which greatly reduces factual errors compared to GPT-5.2. Also, GPT-5.4 introduces native computer-use capabilities, marking a major leap for developers and autonomous agents.
Coastal Sea Levels Higher Than Assumed
A Nature study by researchers from the Netherlands reveals global coastal sea levels are significantly underestimated, averaging about 30cm higher than assumed in some areas. Analyzing 385 publications, they attribute this error to overreliance on geoid models instead of actual measurements, leading to widespread misjudgments of flood risks relative to coastal terrain.